Advancing Responsible AI and Digital Innovation for Global Health
An independent non-profit advancing better healthcare through evidence, innovation and responsible technology.
An independent non-profit advancing better healthcare through evidence, innovation and responsible technology.
The Global Health & Digital Innovation Foundation (GHDIF) works at the interface between healthcare, research, technology and policy. We identify gaps in evidence, measurement, methods and capability that can prevent beneficial innovation from reaching practice, and work with partners to develop, evaluate and apply approaches that can improve healthcare.
GHDIF exists to reimagine the future of healthcare.
Our work brings together clinicians, technologists, standards bodies, policymakers and implementers to close the gap between AI capability and AI accountability in healthcare, with a particular focus on scalable and sustainable innovation.
We support critical innovation to improve the outcomes that matter to patients. DorothAI™ Oncology is an AI-powered platform designed to make breast cancer treatment safer by helping clinicians monitor and manage the risk of cardiotoxicity associated with therapies such as trastuzumab and chemotherapy. By analysing patient data over time,
We support critical innovation to improve the outcomes that matter to patients. DorothAI™ Oncology is an AI-powered platform designed to make breast cancer treatment safer by helping clinicians monitor and manage the risk of cardiotoxicity associated with therapies such as trastuzumab and chemotherapy. By analysing patient data over time, it provides continuously updated risk information, enabling earlier identification of potential heart-related complications and more informed clinical decisions—supporting more personalised care and better long-term outcomes.
DorothAI™ is a clinical intelligence infrastructure platform in formation, being developed as a spin-out of the Global Health & Digital Innovation Foundation (GHDIF).
It explores how governed artificial intelligence and adaptive intelligence can be developed and evaluated for safe use in healthcare. Its initial application focuses on breast cancer care, including cardiotoxicity risk monitoring for patients receiving systemic therapies such as trastuzumab for HER2-positive disease.
GHDIF's non-profit work focuses on the public-benefit evidence, research and healthcare improvement challenges associated with such innovation, while DorothAI™ is being developed as a separate commercial venture.
We are currently inviting NHS and international clinical partners to collaborate on real-world integration alongside standard clinical practice. This includes a pilot programme involving approximately 100–300 patients across 2–3 NHS Trusts to evaluate risk stratification, workflow integration, and adaptive care support in routine oncology settings.
Generating and sharing evidence that can improve healthcare, patient safety and health outcomes.
Supporting the safe, ethical and effective development and use of emerging technologies in healthcare.
Bridging healthcare, research, technology and policy to support responsible innovation and learning.
Supporting approaches that strengthen healthcare systems and extend the benefits of better healthcare across populations.
We work with healthcare providers, researchers, technology developers and policymakers to turn evidence and innovation into safer, better and continuously improving healthcare.
Advancing research on digital health, artificial intelligence, and health data systems, and sharing knowledge openly to improve patient care, public health, and health system performance.
Supporting education and skills development in digital health, AI, and health data governance through workshops, training, and open learning resources.
Bringing together clinicians, researchers, policymakers, and innovators to address complex healthcare challenges through collaboration and responsible innovation.
Promoting inclusive approaches that help ensure digital health technologies benefit underserved communities and support equitable access to care.
Supporting the development of standards and governance frameworks that enable safe, ethical, and trustworthy use of digital technologies in healthcare and public health.
Copyright © 2026 Global Health & Digital Innovation Limited trading as Global Health & Digital Innovation Foundation (GHDIF), All Rights Reserved. GHDIF is a non-profit company limited by guarantee registered in England and Wales with Company Number: 14668242.